Brand Name : Incefo 1.5
Generic Name : Cefoperazone & Sulbactam Injection 1.5 gm
Pack Size : Vial + WFI
Dosage Form : Powder for Injection
Strength : Cefoperazone 1gm + Sulbactam 0.5 gm
Therapeutic indications : Sulbactam/cefoperazone is indicated for the treatment of the following infections when caused by susceptible organisms: Respiratory Tract Infections Urinary Tract Infections (Upper and Lower) Intra-abdominal Infections Septicemia Meningitis Skin and Soft Tissue Infections Bone and Joint Infections Endometritis a Other Infections of the Genital Tract
Pharmacotherapeutic group : Combinations of Cephalosporin and beta-lactamase inhibitors
ATC code : J01DD62
Pharmacodynamic properties : The anti-bacterial component of sulbactam/cefoperazone is cefoperazone, a third generation cephalosporin, which acts against sensitive organisms during the stage of active multiplication by inhibiting biosynthesis of cell wall mucopeptide. Sulbactam does not possess any useful antibacterial activity, except against Neisseriaceae and Acinetobacter. However, biochemical studies with cell-free bacterial systems have shown it to be an irreversible inhibitor of most important beta-lactamases produced by beta-lactam antibiotic-resistant organisms.
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