NIFROM INJECTION

Brand Name : Nifrom

Generic Name : Cefuroxime sodium injection IP

Pack Size : Vial + WFI

Dosage Form : Powder for Injection

Strength : 750 mg & 1.5 gm

Therapeutic indications : Cefuroxime sodium for injection is indicated for the treatment of infections listed below in adults and children, including neonates (from birth).
• Community acquired pneumonia
• Acute exacerbations of chronic bronchitis
• Complicated urinary tract infections, including pyelonephritis
• Soft-tissue infections: cellulitis, erysipelas and wound infections
• Intra-abdominal infections
• Prophylaxis against infection in gastrointestinal (including oesophageal), orthopaedic, cardiovascular, and
gynaecological surgery (including caesarean section)
In the treatment and prevention of infections in which it is very likely that anaerobic organisms will be encountered,
cefuroxime should be administered with additional appropriate antibacterial agents.
Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Pharmacotherapeutic group : antibacterials for systemic use, Second-generation cephalosporins

ATC code : J01DC02

Pharmacodynamic properties : Cefuroxime inhibits bacterial cell wall synthesis following attachment to penicillin binding proteins (PBPs). This results in the interruption of cell wall (peptidoglycan) biosynthesis, which leads to bacterial cell lysis and death.