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Infallible Pharma | P-FOL INJECTION
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Brand Name : P-Fol

Generic Name : Propofol Injection 10mg/ml

Pack Size : Vial

Dosage Form : Emulsion for injection/infusion.

Strength : 100 mg/10ml & 200 mg/20ml

Therapeutic indications : Propofol 10 mg/ml is a short-acting intravenous general anaesthetic agent for
– Induction and maintenance of general anaesthesia in adults and children > 1 month
– Sedation for diagnostic and surgical procedures, alone or in combination with local or regional anaesthesia in adults
and children > 1 month
– Sedation of ventilated patients > 16 years of age in the intensive care unit.

Pharmacotherapeutic group : Anasthetics, general; Other general anaesthetics

ATC code : NOlAXlO

Pharmacodynamic properties : After intravenous injection of Propofol, onset of the hypnotic effect occurs rapidly. Depending on the rate of injection, the
time to induction of anaesthesia is between 30 and 40 seconds. The duration of action after a single bolus administration
is short due to the rapid metabolism and excretion (4-6 minutes).
With the recommended dosage schedule, a clinically relevant accumulation of propofol after repeated bolus injection or after infusion has not been observed. Patients recover consciousness rapidly.
Bradycardia and hypotension occasionally occur during induction of anaesthesia probably due to a lack of vagolytic
activity. The cardio-circulatory situation usually normalises during maintenance of anaesthesia.


February 18, 2022